Dundee scientists solve 3D structure of key protein involved in Intellectual Disability
Scientists at the University of Dundee have identified the effects of a mutation that gives rise to a form of Intellectual Disability.
Intellectual Disability is a type of developmental brain disorder in young patients which to date remains poorly understood and is incurable.
Researchers in the School of Life Sciences at Dundee focussed on mutations in the OGT gene, which plays a critical role in protecting brain cells against stress. In patients harbouring OGT mutations, this protective effect is lost.
Date: 7 April 2018
Source: Drug Discovery Today